JUNBA 2008 Technology Exhibition


Date: January 11th, 2008
Time: 8:30 AM - 6:00 PM Technology Fair Exihibition
Venue: Hyatt Regency Santa Clara, Mezzanine Foyer

Tohoku University

Office of Cooperative Research and Development
Introducing the research activities and Industry-University-Government Collaboration of Tohoku University

Tohoku University celebrated 100th Anniversary on June 2007. Since its inception, the University has embraced its "research-first" and "open-door" policies and puts strong emphasis on education led by prestigious scholars and researchers. In the JUNBA Technology Fair, the University will introduce active promotion of international cooperation among industry, university, and government, through the poster presentation of it as well as Spintronics, Life science, and Biotechnology, its university's one of the representative research activities.

The University of Tokyo

DUCR, The University of Tokyo
Collaborative Research Development to generate “Innovative Outcome” in Global Environment

Overview of the activities of corporate Relations in The University of Tokyo

Tokyo Institute of Technology

Introduction of International Collaborative Activities with Industry by Tokyo Institute of Technology: Its Research Alliance Program and Potential Technologies for Licensing

Tokyo Institute of Technology (Tokyo Tech) is moving to one of the world's leading research universities in the pursuit of advanced science and technology. In order to improve/maintain Tokyo Tech's research capability, Tokyo Tech encourages its faculty members to collaborate with not only Japanese industry but also foreign industry. As a part of such activities, Tokyo Tech is conducting several collaborative researches under research alliance agreement with particular organizations.

For one example of the research alliances, Tokyo Tech made an agreement with Microsoft Corporation in order to promote Tokyo Tech's research agenda in various domains, including environmental science, health care, chemical engineering, nano-technology and computer science. Theme of current collaborative research is "Large-scale Commodity Accelerated Clusters and Its Application to Advanced Structural Proteomics"

Apart from the research alliance, Tokyo Tech also licenses its own international patent to foreign companies. One of the promised technologies is "atmospheric pressure plasma technique" that is one of advanced base technologies to solute environmental problems. This technology can perform decomposition of the chlorofluocarbon, halon and PFC, recycling of waste plastic, and collecting indium from waste liquid crystal panels, etc. without energy consumption.

Osaka University

Growing Start-ups and Technology Transfer from Osaka University

Osaka University has been striving to enhance Industry-Academia-Government Collaboration in various fields. With the establishment of Intellectual Property Office in 2004 as a turning point, Osaka University has actively pursued several projects for utilization of university's intelligence to social needs, through activities of its organizations newly formed to achieve this objective, such as Organization for University, Industry and Government Cooperation, as well as Division of Global Industry-Academia-Government Strategic Collaborations.

At Technology Fair, we will be happy to report on our activities, centered with introduction of Start-ups and Intellectual Properties from Osaka University.

Tokyo University of Agriculture and Technology

Aiming at Global Partnership: Introduction of TUAT's Activities in Industry-Academia Collaboration and Research Projects

Tokyo University of Agriculture and Technology (TUAT) focuses its education and research in agriculture and technology as well as in their interdisciplinary fields. TUAT regards industry-academia collaboration as a driving force to improve the quality of both education and research, and to innovate new technology for contributing to the society as a whole. According to the surveys conducted by Nihon Keizai Shimbun Inc. in 2004, TUAT was ranked top in terms of its capacity to disseminate research results, fifth in the formation of industry-academia collaboration, and fifth in its overall research capabilities. In 2005, TUAT was selected as one of six (6) universities by MEXT* for the Super Industry-Academia-Government Collaboration Headquarters Program. In 2007, a regional incubator was approved to be built, which is first in Tokyo and first with the existing Campus Incubator in the same campus. Moreover, TUAT was selected as one of twelve (12) universities under MEXT's new program for the promotion of international industry-academia-government collaboration.

With these track records and cutting-edge technologies developed at TUAT, it is now making utmost efforts to enhance global collaborations. The presentation highlights TUAT's activities in industry-academia collaboration, venture creation, a brief overview on TUAT's technologies by research categories, etc. At the exhibition booth, TUAT's Research Coordinator will explain in more details a variety of research projects for future collaboration.

*MEXT: Ministry of Education, Culture, Sports, Science and Technology

Hokkaido University

Uniting Top-down and Bottom-up Systems on Clean Unit System Platform (CUSP)

Aiming at developing TD (top-down) - BU (bottom-up) unification platform being crucial to harvest fruits made by upcoming nano-science and bio-technologies as well as Si-LSI -based information devices, we have reached at such byproducts as quantum-cross memory, high efficiency solar cell, and clean unit system platform (CUSP) upon which those new devices are processed. The CUSP helps you perform not only TD nor BU processes but also TD-BU unification with the world's highest cleanliness, ISO class -1, no matter how dusty the ambience is.

Kyoto University

Kyoto University's Activity of Industrial-Academic Collaboration

Introduce the organization of KU for the support services for collborative researches, intellectual property, venture-business nurturing, and international collaborative activities.
Introduce some of the KU's technology seeds.
Introduce KU's "researcher-database" and show how to access.
Introduce the organization of KU for the support services for collborative researches, intellectual property, venture-business nurturing, and international collaborative activities.
Introduce some of the KU's technology seeds.
Introduce KU's "researcher-database" and show how to access.

Kyushu University

MIMO-MESH project overview and exhibition of picoMESH node

We overview MIMO-MESH project, a 5-year project supported by Fukuoka IST and Ministry of Education, Culture, Sports, Science and Technology of Japanese government. Objective of the project is to develop a key infrastructure for ubiquitous broadband mobile communication systems in future. We are developing wireless access nodes in palm size with capability of providing high capacity mesh networking. This tiny node, we call it as picoMESH, can reduce deployment cost for setting up broadband wireless infrastrucutres by its great portability. Some picoMESH nodes will be present at the conference booth.

Tokyo University of Science

1. About TUS Technology Licensing Organization (RIDAI SCITEC)
2. Direct Thermal-to-Electric Conversion
3. Nanoimprint technology, Electron beam lithography and Nano-mold fabrication process
4. SQAG: Potent Novel Radiosensitizer

Following the introduction of Technology Licensing Organization of Tokyo University of Science, three research seeds will be presented by researchers themselves.

Seed 1: Faculty of Industrial Science and Technology: Associate Professor Tsutomu Iida, Ph.D: In order to control the global warming, we have developed a new technology using Mg2Si reproduced from discarded silicon for thermal-to-electric energy conversion materials. Based on this technology we are now challenging the practical mass production of these materials.

Seed 2: Faculty of Industrial Science and Technology: Associate Professor Jun Taniguchi, Ph.D: The term of "Nanotechnology" introduced by Tokyo University of Science is now worldwide and "Nanoimprint Technology" is one of cutting edge technology in this field. Using this technology, we have succeeded the development of production system of sub-micron optical plates and anti-reflection structures.

Seed 3: Genome and Drug Research Center: Fumio Sugawara, Ph.D: A novel potent radiosensitizer, SQAG, targeting tumor angiogenesis has been identified. The agent remarkably enhances the radioresponse of human tumors transplanted into nude mice, accompanied by a significant reduction in the vascularity of the tumors. Target identifications were performed by phage display screening and DNA microarray to lead us to expectation of cancer radiation therapy.

Ritsumeikan University

1. Color Science and its application to color-barrier- free products
2. Development of a New Anti-Inflammatory Drug that Reduces Nitric Oxide Production
3. Fabrication of nonlinear photonic crystal and its application

1. Taking up UD Color (Color-Barrier-Free Software for color vision deficiency) and CRS (Color Recovery Lighting System to prevent the perceptive color loss for cataractous elderly people), the product development using color science and psychophysical approaches are introduced. They are outcome of joint researches with companies. CRS was awarded GOOD DESIGN AWARD by Japan Industrial Design Promotion Organization in 2005.

2. During inflammation or injuries, the inflammatory mediator nitric oxide is produced. In the stimulated hepatocytes, inducible nitric oxide synthase (iNOS) is synthesized to generate nitric oxide. When the functional food AHCC was added to the hepatocytes, the iNOS mRNA level decreased. We also found that an antisense transcript from iNOS gene had effects on the stability of iNOS mRNA. The post-transcriptional mechanism by antisense transcripts may be a new target of an anti-inflammatory drug.

3. If we could fabricate photonic crystal with nonlinear optical property, we can expect giant nonlinearity in this photonic crystal. We have realized the giant nonlinearity of photonic crystal using newly developed hetero-structure photonic crystal. The enhancement of the nonlinearity in the photonic crystal has been more than 300 times compared with conventional nonlinear materials. In this presentation we demonstrate all optics light modulator or switch using this hetero structure photonic crystal.

Kagoshima University

Design of protein function-mimicking peptides and therapeutic human antibodies by phage library

Phage display is a technique which can enable to display the foreign peptides or proteins on the surface of the bacteriophages by introducing their genes into the genome of phage or phagemid DNA. By using this technique, we constructed a huge human naive antibody (single chain Fv, scFv) library or random peptide library to isolate a specific antibodies or bioactive peptides especially for therapeutic application. In the anterior half of this presentation, I will report the isolation of scFv specific to ATL (Adult T cell Leukemia)-derived cancer cell line, S1T cells from antibody phage library and its characterization inducing apoptotic cell death on S1T cells. In the posterior half, the isolation of a small peptide which specifically binds to human IgG Fc from random peptide library will be reported. Such peptides can be potentially used for the purification process in the production of human therapeutic antibody as an affinity ligand and also for detection of human antibody in the clinical assay. Our phage display libraries can be applied to find new affinity ligands targeting not only disease-related molecules in human therapy but also organic or inorganic materials for material science.

ORIGINAL BIOTECHNOLOGIES AND THEIR APPLICATION IN GENE THERAPY AND REGENERATIVE MEDICINE: mainly, conditionally replicating adenoviruses that specifically target cancer with multiple tumor-specific factors

Although a conditionally replicating adenovirus (CRA) exhibiting cancer-selective replication and induction of cell death is an innovative potential anticancer agent, current imperfections in cancer specificity and efficient viral replication limit the usefulness of this technique. Although a promising approach to circumvent this obstacle is to introduce multiple tumor-specific factors into a single CRA, CRAs regulated with a multiple tumor-specific factors (m-CRAs) have not been successfully developed due to the lack of standardized methods to efficiently generate even a current CRA regulated with a single factor. We first developed an innovative method for efficiently, rapidly and feasibly constructing diverse m-CRAs, and solved this problem. Using our original method for efficiently constructing m-CRA, we first developed survivin-responsive m-CRAs (Surv.m-CRA), and are now developing several types of new m-CRAs, which are attractive potential anticancer agents. We have a plan to start up a venture business in March, 2010. One of our business plans is to sell made-to-order m-CRAs for researchers in the world, particularly, in USA, Japan and EU. Because we have the patent of Surv.m-CRA as an anticancer agent and other ones regarding innovative medicine and/or therapy; e.g., gene medicine that treats myocardial infarction, regenerative medicine that potently treats liver diseases, biotechnology in embryonic stem cell-based regenerative medicine, we hope to successfully extend our initial venture business toward pharmaceutical developer and supplier. We are seeking for collaborative facilities and institutes in USA to cooperate in the business of m-CRA (supplying made-to-order GLP and GMP m-CRAs to researches and clinician in USA) and clinical trials of such innovative therapies.

Nanoparticle Anti-AIDS Vaccine

We have created novel biodegradable nanoparticles (NPs) from poly(γ-glutamic acid) (γ-PGA). Various proteins and peptides can be immobilized onto and/or encapsulated into the NPs. The NPs act as an efficient antigen carrier to dendritic cells (DCs) and capable of activating DCs. Consequently, the antigen-carrying NPs are capable of inducing strong immune responses to protein antigens, such as human immunodeficiency virys type 1 (HIV-1) gp120 and p24, in amimal models. Thus, γ-PGA NPs carrying various HIV-1 proteins and/or peptides may be a great potential as a novel anti-AIDS vaccine.

Creation of a new flower color

This session focuses on heredity of the biosynthesis of flower pigments and the relationship between flower color and pigment genotype, thereby providing a method of crossing flower color genotypes which is practically available in creating a new flower color. The method is based on a novel rule that flower color genotypes represented by heredity of flavonoid B-ring hydroxylase are under the control of multiple alleles.

Nara Institute of Science and Technology

Surgical Simulation

This demonstration presents surgical-template-based surgical simulation for supporting preoperative planning with easy set-up from patient CT/MRI volume data. We also developed surface-constraint-based manipulation techniques that robustly simulate common surgical manipulations such as grasping, holding, cutting and retraction. Our new volume manipulation framework allows surgeons to interactively manipulate soft models like through surgical tools. We applied our techniques to various CT volume dataset on general purpose PC, and achieved interactive response in volume manipulation. Several surgical approaches and procedures were rehearsed and used for preoperative discussion.

Yokohama City University


University of Yamanashi

Technical seeds related to Fuel Cell & University Consortium for International Intellectual Property Coordination (UCIP)

1. Technical seeds related to Fuel Cell

Clean Energy Research Center has one of the best techniques in the world in terms of fuel cell. Many great results have been achieved. We will introduce patents on fuel cell owned by University of Yamanashi as well as researches and approaches for practical use of Polymer Electrolyte Fuel Cell (PEFC) which the research center has been promoted.

2. University Consortium for International Intellectual Property Coordination (UCIP)

University Consortium for International Intellectual Property Coordination (UCIP) was jointly established by University of Yamanashi and Niigata University in June 2007 as an interuniversity network to promote global industry-academia-government collaboration of small-to-medium sized universities. UCIP has functions which universities can share useful information as well as common issues and complement each other.

Nagoya University

The introduction of industry-university cooperation activity and the reserch seeds of Nagoya University

Nagoya University moves into action aiming at social contribution through leading-edge scientific study. As an example, We introduce the following contents through a panel exhibition.

・Headquarter for Industry,Academia and Government Cooperation
・High Voltage Electron Microscope Laboratory
・Tokai Bio Factory Project
・Nagoya University Synchrotron radiation Research Center